Publications by authors named "E Kosik"

Changes in neural activity thought to reflect brain aging may be partly influenced by age-dependent signals 'leaking' from the heart.

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  • The human face is essential for expressing emotions and social interaction, but the brain's structural connections to these facial expressions are still unclear.
  • A study of 55 older adults linked specific facial behaviors, like frowning or smiling during emotional videos, to increased gray matter volume in brain regions associated with emotional and motor functions.
  • The results indicate that both emotional and motor brain networks physically represent facial expressions, highlighting the midcingulate cortex's role in coordinating these facial movements during emotions.
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Major depressive disorder (MDD) is a leading cause of disability worldwide. One of the most efficacious treatments for treatment-resistant MDD is electroconvulsive therapy (ECT). Recently, magnetic seizure therapy (MST) was developed as an alternative to ECT due to its more favorable side effect profile.

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  • Semantic dementia (SD) involves deterioration of the anterior temporal lobes, leading to loss of semantic knowledge and changes in social-emotional behavior, with two clinical variants: svPPA and sbvFTD, differing by the hemisphere affected.
  • A study compared resting autonomic nervous system activity (measured through respiratory sinus arrhythmia and skin conductance) among 82 participants, including those with SD and healthy controls, finding lower levels in SD individuals.
  • The research indicated that the left-sided brain atrophy in SD correlates with reduced autonomic function and diminished social behavior, with specific areas of atrophy linked to lower parasympathetic and sympathetic activity.
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