Publications by authors named "E Konishi"

Tenosynovitis with psammomatous calcification (TPC) is an extremely rare condition. It was first described as a characteristic subtype of idiopathic calcifying tenosynovitis, with only 40 cases reported to date. Here, we present a case of TPC affecting a female patient in her late teens, with no relevant medical history.

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Sarcoidosis is a multisystemic and chronic inflammatory disorder characterized by the manifestation of epithelioid cell granulomas in various organs. Sarcoid-like reactions occur in patients who do not fulfill the diagnostic criteria for sarcoidosis but present with similar clinical and histological features. An 80-year-old man presented to our hospital with several subcutaneous nodules on the extremities.

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Primary neuroendocrine carcinoma (NEC) of the anal canal is a rare, highly malignant tumor with a poor prognosis. Despite the standard first-line treatment with etoposide or irinotecan combined with cisplatin, effective second-line therapies are lacking. In 2019, Japan approved cancer genome profiling (CGP) tests for solid tumors to enhance genomic understanding.

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In ALK-negative anaplastic large cell lymphoma (ALCL), gene rearrangements of and are considered mutually exclusive. The former predicts a favorable prognosis, while the latter is generally unfavorable. We report the first case of ALK-negative ALCL in a leukemic phase with small cell pattern transformation, harboring double-hit rearrangements of the gene by inv(6)(p25q21) and gene by TBL1XR1-TP63 inversion.

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Article Synopsis
  • - A 65-year-old man had endoscopic treatment for esophageal cancer and was later found to have a suspicious 12-mm flat lesion in his stomach during a surveillance endoscopy.
  • - The lesion was examined with magnifying endoscopy and biopsy revealed atypical cells, leading to a diagnosis of a gastric-type neoplasm with low atypia.
  • - Following further investigation, endoscopic submucosal dissection (ESD) led to a diagnosis of signet-ring cell carcinoma that transformed into adenocarcinoma of the fundic gland type, highlighting the complexity of his condition.
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