Publications by authors named "E Kondo"
Although the energy stored in the lean tissue (LT) and adipose tissue (AT) is well known, the energy required to synthesize these tissues is obscure. Theoretically, the energy at the point at which ΔLT/Δ body weight (BW) reaches 100% on a regression line, which indicates the relationship between ΔLT/ΔBW and the energy required for BW gain, is considered to be the energy expended to synthesize LT. Therefore, we investigated this relationship in rats.
View Article and Find Full Text PDFBackground: Soft-tissue sarcomas (STSs) are a diverse group of malignancies challenging to treat when surgery is not an option. The aim of this study was to investigate the survival of non-surgical cases in STSs, and to examine the impact of radiation therapy (RT) on survival within this group of cases.
Methods: Utilizing the SEER database, we conducted a retrospective cohort study of localized extremity non-small round cell sarcoma diagnosed between 2000 and 2019.
Article Synopsis
- * The neutrophil cytosolic factor-1 (NCF-1) is identified as a key ROS-generating protein and has been primarily studied in immune cells, but its expression and function in cancer, particularly pancreatic and gastric cancers, was not well understood.
- * This study found that NCF-1 is highly expressed in pancreatic and gastric cancer cells, where it promotes tumor growth and survival, suggesting that NCF-1-related ROS generation is essential for these cancers, contrary to the typical view of ROS as solely harmful
Background: Periprosthetic joint infections (PJIs) following total knee arthroplasty (TKA) are among the most challenging pathologies to manage. Recently, continuous local antibiotic perfusion (CLAP) therapy has been introduced for treating musculoskeletal infections in orthopedics. This study aimed to determine the outcomes and risks of CLAP therapy combined with conventional treatment for PJIs after TKA.
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- The study aimed to investigate why pregnant women with glucose intolerance often have large infants, focusing on amino and fatty acid transport in the placenta, beyond just glucose transport.
- Researchers analyzed postpartum placental tissues from 101 eligible deliveries, finding higher expression levels of certain transporters (LAT1 and placenta-FABPpm) in women with glucose intolerance compared to those without.
- The results suggest that, despite controlled blood sugar levels, managing other nutrients like amino acids and fatty acids in glucose-intolerant pregnancies is crucial for fetal growth.