Characterization of clustered bacteriocin-type signal domain protein genes in .

Background: Periodontitis is caused by the dysbiosis of subgingival plaque, and is the pathogen associated with this disease. Bacteriocins are involved in interbacterial competition during dysbiosis. In our previous study, three potential bacteriocin ABC transporter genes ( and of were investigated.

Treponema Denticola Activates NF-κB Pathway via Toll-like Receptor 2.

Treponema denticola is frequently isolated together with Porphyromonas gingivalis from the lesions seen in cases of chronic periodontitis and is considered a major pathogen of this disease. It has several virulence factors, including a major surface protein (Msp) and a major surface protease, dentilisin. The effect of these virulence factors on the host immune response remains to be elucidated, however.

Effect of Porphyromonas Gingivalis Infection on Epithelial Rests of Malassez.

The epithelial cell rests of Malassez (ERM) are located within the periodontal ligament. They are reportedly involved in maintaining homeostasis, particularly with regards to the thickness of the periodontal ligament. Their role in apical periodontitis lesions remains unclear, however.

Anisotropic patterns of nanospikes induces anti-biofouling and mechano-bactericidal effects of titanium nanosurfaces with electrical cue.

Anti-microbial nanopatterns have attracted considerable attention; however, its principle is not yet fully understood, particularly for inorganic nanopatterns. Titanium nanosurfaces with dense and anisotropically patterned nanospikes regulate biological functions with multiple physical stimulations, which may be because of the nanopattern-induced alternation of surface physical properties. This study aimed to determine the antimicrobial capability of titanium nanosurfaces and their mechanisms.