Publications by authors named "E Kjeldsen"
The escalating prevalence of dementia worldwide necessitates preventive strategies to mitigate its extensive health, psychological, and social impacts. As the prevalence of dementia continues to rise, gaining insights into its risk factors and causes become paramount, given the absence of a definitive cure. Cardiovascular disease has emerged as a prominent player in the complex landscape of dementia.
View Article and Find Full Text PDFBackground: Telomeropathies are a group of inherited disorders caused by germline pathogenic variants in genes involved in telomere maintenance, resulting in excessive telomere attrition that affects several tissues, including hematopoiesis. RecQ and RTEL1 helicases contribute to telomere maintenance by unwinding telomeric structures such as G-quadruplexes (G4), preventing replication defects. Germline RTEL1 variants also are etiologic in telomeropathies.
View Article and Find Full Text PDFAim: Due to aging populations the incidence of aortic valve stenosis (AVS) is increasing steeply. Since no medical therapy is available but only surgical interventions, it is highly warranted to identify modifiable risk factors for early prevention. The aim of the study was to investigate the associations of cardiovascular risk factors with AVS and to create 10-year absolute risk scores for use in primary prevention.
View Article and Find Full Text PDFBackground: It is unknown if an unhealthy diet can affect the risk of developing psoriasis.
Objectives: To test the hypothesis that individuals with an unhealthy diet have an increased risk of prevalent and incident psoriasis.
Methods: We included 105 332 adults from the Copenhagen General Population Study, who were invited to participate between 2003 and 2015.