Publications by authors named "E Kiryanova"
The ANKK1/DRD2 gene TaqIA polymorphism (rs1800497) is associated with the severity of extrapyramidal side effects of haloperidol treatment in CYP2D6 extensive metabolizers with schizophrenia spectrum disorders.
Drug Metab Pers Ther
June 2023
Objectives: Extrapyramidal symptoms (EPS) are one of the most prominent side effects of haloperidol. Variability of EPS severity may be associated with the genetic factors, affecting both haloperidol pharmacokinetics (e.g.
View Article and Find Full Text PDF[Efficiency of erenumab in neurologist's real practice].
Zh Nevrol Psikhiatr Im S S Korsakova
August 2022
Article Synopsis
- The study assessed the real-life effectiveness and safety of erenumab in treating migraine in 33 patients, primarily females with an average age of 39.2 years.
- During the treatment, a significant 50% reduction in headache days was reported by nearly half of the patients across the first three months, along with improvements in pain intensity and the impact on daily activities as measured by HIT-6 scores.
- Side effects were minimal, with only one instance of transient constipation, suggesting that erenumab is both effective and safe for outpatient use in managing migraines.
The article is devoted to the work of the Moscow Research Institute of Psychiatry to improve psychiatric care for patients with psychotic disorders. An important feature of this work was an integrated approach, in which the clinical picture of the disease was assessed in close connection with the patient's personal and psychological characteristics, social conditions of his life, therapeutic opportunities, rehabilitation potential and organizational structure of care. The article reflects the results of many years of work of the department of outpatient psychiatry and the organization of psychiatric care under the guidance of Professor I.
View Article and Find Full Text PDFNeurocognition and social cognition are the core deficits influencing social outcomes in patients with schizophrenia. These deficits are present in the prodromal phase, throughout the illness and in first-degree relatives. They are considered in the framework of neurodevelopmental or neurodegenerative models as well as candidates for endophenotypes of schizophrenia.
View Article and Find Full Text PDFBackground: Resistance to second-line drugs develops during treatment of multidrug-resistant (MDR) tuberculosis, but the impact on treatment outcome has not been determined.
Methods: Patients with MDR tuberculosis starting second-line drug treatment were enrolled in a prospective cohort study. Sputum cultures were analyzed at a central reference laboratory.