Publications by authors named "E Kirstine Lyhne"
Article Synopsis
- The text discusses industrial biotechnology applications, focusing on the production of itaconic acid and bioactive metabolites from specific fungal species.
- Draft genome sequences were presented for multiple species, revealing a rich diversity of secondary metabolism genes, particularly in one genus, which shows high potential for genome mining.
- The study found unique strategies for UV protection among these species and highlighted their impressive ability to degrade plant polysaccharides, indicating further biotechnological uses.
Article Synopsis
- - Section Flavi includes both harmful (e.g., Aspergillus flavus) and beneficial (e.g., Aspergillus oryzae) species of fungi, with the latter playing a role in food fermentation and enzyme production.
- - Researchers sequenced 19 genomes and compared them to others, finding that the closest relative of A. oryzae is not A. flavus but rather A. minisclerotigenes or A. aflatoxiformans, revealing high genetic diversity, especially near chromosome ends.
- - Although many CAZymes and secondary metabolite genes are predicted in section Flavi, the correlation between these predictions and actual growth characteristics or polysaccharide breakdown is inconsistent, indicating a
Aspergillus section Nigri comprises filamentous fungi relevant to biomedicine, bioenergy, health, and biotechnology. To learn more about what genetically sets these species apart, as well as about potential applications in biotechnology and biomedicine, we sequenced 23 genomes de novo, forming a full genome compendium for the section (26 species), as well as 6 Aspergillus niger isolates. This allowed us to quantify both inter- and intraspecies genomic variation.
View Article and Find Full Text PDFThe fungal genus of is highly interesting, containing everything from industrial cell factories, model organisms, and human pathogens. In particular, this group has a prolific production of bioactive secondary metabolites (SMs). In this work, four diverse species (, , , and ) have been whole-genome PacBio sequenced to provide genetic references in three sections.
View Article and Find Full Text PDFArticle Synopsis
- Several species in Aspergillus section Nigri have been known to produce sclerotia, which are crucial for sexual development, but Aspergillus niger has traditionally been viewed as asexual until recent findings.
- For the first time, certain strains of Aspergillus niger were found to produce sclerotia when grown on Czapek yeast autolysate agar with raisins and other fruits, leading to the detection of new secondary metabolites.
- Additionally, the study showed that raisins can induce sclerotium formation in various other black Aspergillus species for the first time, expanding understanding of their growth and metabolite production.