Publications by authors named "E Khafipour"

Maternal diet may modulate human milk microbiota, but the effects of nutritional supplements are unknown. We examined the associations of prenatal diet and supplement use with milk microbiota composition. Mothers reported prenatal diet intake and supplement use using self-administered food frequency and standardised questionnaires, respectively.

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Background: High-yielding dairy cows are commonly fed high-grain rations. However, this can cause subacute ruminal acidosis (SARA), a metabolic disorder in dairy cows that is usually accompanied by dysbiosis of the rumen microbiome. Postbiotics that contain functional metabolites provide a competitive niche for influential members of the rumen microbiome, may stabilize and promote their populations, and, therefore, may attenuate the adverse effects of SARA.

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Article Synopsis
  • Subacute ruminal acidosis (SARA) is a metabolic disorder commonly affecting high-yielding dairy cows, leading to changes in their rumen microbiome and increased inflammation. This study tested two postbiotics derived from Saccharomyces cerevisiae fermentation on cows experiencing repeated SARA challenges after giving birth.
  • The research involved 32 rumen-cannulated cows divided into four treatment groups, including a control diet and different levels of postbiotic supplements, assessing their effects on rumen microbiota through DNA sequencing.
  • SARA challenges were found to decrease the diversity and functionality of the rumen microbiota, while postbiotic supplementation, particularly with SCFPb-2X, helped maintain microbi
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Background: It is vital to understand healthy gut microbiota composition throughout early life stages when environments are changing, and immunity is developing. There are limited large-scale longitudinal studies classifying healthy succession of swine microbiota. The objectives of this study were to (a) determine the microbiota composition of fecal samples collected from piglets within a few days after birth until one-week post-weaning, and (b) investigate the associations of early fecal microbiota with pig growth performance in nursery and later growing stages.

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The yeast-based postbiotic EpiCor is a well-studied formulation, consisting of a complex mixture of bioactive molecules. In clinical studies, EpiCor postbiotic has been shown to reduce intestinal symptoms in a constipated population and support mucosal defense in healthy subjects. Anti-inflammatory potential and butyrogenic properties have been reported , suggesting a possible link between EpiCor's gut modulatory activity and immunomodulation.

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