Publications by authors named "E Kendjo"
Objectives: There is little data on pregnant women with imported malaria in high-income countries, especially regarding offspring outcomes. We wanted to determine pregnancy outcomes of imported malaria in pregnant women in mainland France.
Patients And Methods: We conducted a retrospective, descriptive study of outcomes in pregnant women hospitalized with malaria from 2004 to 2014 in two regions of mainland France.
Article Synopsis
- Positive direct antiglobulin tests (DATs) were found in a study on post-artesunate delayed hemolysis (PADH), but the relationship between DAT positivity and PADH is not clear.
- In a 7-year study of 337 severe malaria patients treated with artesunate, 54.3% of those who had DAT results experienced positive results, yet this did not correlate with the occurrence of PADH.
- The findings suggest that DAT positivity is not a reliable marker for PADH and should not prompt the use of corticosteroids in treatment.
Background: The impact of chemoprophylaxis targeting Plasmodium falciparum on Plasmodium vivax and Plasmodium ovale, which may remain quiescent as hypnozoites in the liver, is debated.
Methods: We conducted a nested case-control analysis of the outcomes of P. vivax and P.
Article Synopsis
- An electronic surveillance system was implemented in France to monitor the incidence of imported malaria cases and assess the sensitivity of malaria isolates among travelers.
- The study evaluated the system based on the quality of surveillance, early warning capacity for public health events, and healthcare practitioners' usage of the online system.
- Results showed a significant improvement, with the time to report cases dropping from about 227 days in 2006 to just 2 days in 2020, proving the system's effectiveness for future malaria research.
In acute malaria, the bulk of erythrocyte loss occurs after therapy, with a nadir of hemoglobin generally observed 3-7 days after treatment. The fine mechanisms leading to this early post-treatment anemia are still elusive. We explored pathological changes in RBC subpopulations by quantifying biochemical and mechanical alterations during severe malaria treated with artemisinin derivatives, a drug family that induce "pitting" in the spleen.
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