Publications by authors named "E Kazakov"
Combined proton-neutron therapy can be the best opportunity for neutron radiation therapy due to highly conformal proton irradiation and high relative biological effectiveness of neutrons. The study compares 4 schemes of sequential in vitro exposure of Chinese hamster fibrosarcoma cells B14-150 to 14.5 MeV neutrons and a scanning beam of protons.
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- The study focuses on how plants respond to extreme conditions like microgravity and radiation, which is important for space exploration and improving plant resilience in outer space.
- Researchers created a 3D clinostat to replicate microgravity conditions and used proton irradiation to simulate space conditions, studying the effects on plant seeds from the Chernobyl exclusion zone.
- Results showed that one plant type was resilient to these conditions, while others experienced inhibited photosynthesis; findings and tools developed are available for further research in space biology.
Comparative Analysis of the Effect of Gamma-, Electron, and Proton Irradiation on Transcriptomic Profile of L. Seedlings: In Search for Molecular Contributors to Abiotic Stress Resilience.
Plants (Basel)
January 2024
Article Synopsis
- - The study focuses on developing crop adaptation strategies in response to climate change, specifically through investigating barley's reaction to ionizing radiation as a means to understand stress resilience.
- - Researchers identified 553 genes that were upregulated and 124 downregulated in barley seedlings after exposure to different types of radiation, with the highest activity seen in samples exposed to electrons.
- - Key genes relating to stress responses, such as those involved in DNA repair, ROS response, and photosynthesis, were significantly activated, suggesting that understanding these pathways could enhance plant stress tolerance in agriculture.
The recent advances achieved in microscopy technology have led to a significant breakthrough in biological research. Super-resolution fluorescent microscopy now allows us to visualize subcellular structures down to the pin-pointing of the single molecules in them, while modern electron microscopy has opened new possibilities in the study of protein complexes in their native, intracellular environment at near-atomic resolution. Nonetheless, both fluorescent and electron microscopy have remained beset by their principal shortcomings: the reliance on labeling procedures and severe sample volume limitations, respectively.
View Article and Find Full Text PDFAn electrochemical hydrogen pump (EHP) with a proton exchange membrane (PEM) used as part of fusion cycle systems successfully combines the processes of hydrogen extraction, purification and compression in a single device. This work comprises a novel study of the effect of ionizing radiation on the properties of the PEM as part of the EHP. Radiation exposure leads to nonspecific degradation of membranes, changes in their structure, and destruction of side and matrix chains.
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