Iodide supplementation: 200 micrograms daily or 1,500 micrograms weekly?

25 euthyroid volunteers were divided into two groups. Each participant of group A received 200 micrograms iodine in the form of diiodotyrosine per day for a period of eight weeks, i.e.

Hyperthyroidism with or without pyramidal lobe Graves' disease or disseminated autonomously functioning thyroid tissue?

I-123 thyroid scintigrams performed in 349 patients were evaluated with a focus on specific thyroid gland vestiges, namely a pyramidal lobe or a thyroglossal duct. The detection of these vestiges in patients with hyperthyroidiam is indicative of autoimmune hyperthyroidism. In Graves' disease, stimulating thyrotropin (TSH) receptor antibodies cause a significantly more frequent appearance of vestiges of the thyroglossal tract.

Bennhold's analbuminemia: a follow-up study of the first two cases (1953-1992).

A pair of siblings with analbuminemia were followed for 38 years. The female patient received replacement therapy with human serum albumin. Extreme lipodystrophy developed in this patient by the fourth decade of life.

[Iodine content in diet and excretion of iodine in urine].

The standard food for our volunteers, prepared in the central kitchen of the University Hospital of Tubingen, consisted of breakfast, warm lunch and cold supper and contained, on average, approximately 230 micrograms of iodine/day. It is generally assumed that an equilibrium is established between iodine intake from food and urinary iodine excretion. Hence, the amount of iodine excreted with the urine within 24 h may reflect the daily ingestion of iodine.

Inhibitory and disruptive effects of some antirheumatics on antigen-antibody complexes.

Purified antibodies to human serum albumin or to human gamma-globulin were used to study the direct influence of some antirheumatic drugs on the formation and disruption of immunoprecipitates. 125I-labelled human serum albumin and 125I-labelled human IgG served as indicators. The effects of the following drugs were described: diclofenac, monophenylbutazone, diphenylbutazone, ibuprofen, and metamizol.