Publications by authors named "E Kabartan"
Article Synopsis
- Scientists studied how a substance called alpha-pinene (AP) could help protect the heart and liver from damage caused by a medicine called methotrexate (MTX).
- They tested this by using rats and found that MTX caused a lot of harm to the heart and liver, but when the rats got AP before the MTX, the damage was much less.
- This suggests that alpha-pinene might be a helpful way to protect the heart and liver during cancer treatments that use methotrexate.
The purpose of the study was to investigate whether the promoter methylation status of BRCA1 and BRCA2 DNA repair genes is associated with sperm DNA fragmentation (sDF) in infertile men with oligoasthenoteratozoospermia (OAT) which emerges due to various reasons and is effective in male infertility. Seventy-three infertile men with OAT and 20 normozoospermic volunteers participated in the study. To investigate sDF and methylation patterns of BRCA1 and BRCA2 gene promoters, TUNEL assay and methylation-specific PCR (MS-PCR) were used.
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