Publications by authors named "E K Vishnevskaia"

New methodological approaches to preclinical study of the efficiency of potential prostatotropic drugs are suggested on the basis of original research and published data. An algorithm is proposed to investigate specific activity and safety of potential drugs for the prevention and treatment of prostate disorders.

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Methodological approaches to preclinical evaluation of the efficiency of potential dermotropic preparations are proposed on the basis of original investigations and an analysis of published data. At the first stage of the preclinical investigation of preparations for external application, it is necessary to estimate their acute toxicity, allergenic activity, and local irritation effect in addition to studying the specific activity.

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Article Synopsis
  • The viability and enzymatic activity of pathogens in extrapulmonary tuberculosis are significantly lower compared to those in pulmonary tuberculosis, indicating a potential difference in disease severity.
  • The use of mycobacterial L-forms and polymerase chain reaction has improved the diagnosis of extrapulmonary tuberculosis cases.
  • Drug resistance is less common in extrapulmonary tuberculosis, with lower multidrug resistance rates and preserved levofloxacin sensitivity, suggesting better treatment options.
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195 reproductive patients (23-29 years--6.2%, 40-45 years--57.4%) were treated for endometrial carcinoma.

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Data are presented on screening for cervical (CC), endometrial (UC) and ovarian (OC) carcinoma carried out in the Republic of Belarus as well as a discussion of logistic and methodologic aspects of the problem. Local "centers for prevention and early diagnosis of reproductive organ tumors" form the backbone of the national system. They operate on the basis of the existing guidelines about such matters as screening staging, sites, examination procedures used at each stage and suitable distribution of medical personnel (obstetricians, doctor's assistants, gynecologists).

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