Comparisons of neurodegenerative disease biomarkers across different biological fluids from patients with Huntington's disease.

Fluid biomarkers play important roles in many aspects of neurodegenerative diseases, such as Huntington's disease (HD). However, a main question relates to how well levels of biomarkers measured in CSF are correlated with those measured in peripheral fluids, such as blood or saliva. In this study, we quantified levels of four neurodegenerative disease-related proteins, neurofilament light (NfL), total tau (t-tau), glial fibrillary acidic protein (GFAP) and YKL-40 in matched CSF, plasma and saliva samples from Huntingtin (HTT) gene-positive individuals (n = 21) using electrochemiluminescence assays.

Effect of blindfolding the lead resuscitator on frequency of closed-loop communication during veterinary cardio-pulmonary resuscitation training: a randomized, controlled pilot study.

Objective: To evaluate the effect of blindfolding the lead resuscitator during veterinary cardiopulmonary resuscitation (CPR) simulation training sessions on frequency of completed closed-loop communication statements (CLC).

Design: Ten groups of staff volunteers were recruited for a prospective, randomized, blinded, observational pilot study over a 6-month period. Additionally, two associated online questionnaires were completed by participants.

Examining the Proximal Relationship between Religious Coping and Depression among Trauma-Exposed Adults.

Depression is a common consequence of sexual victimization. Although religious coping has been previously studied within the context of sexual victimization, there is a dearth of research examining the potential reciprocal relationships between religious coping and depression among adults with a history of sexual victimization at the daily level. The current study addresses this important gap by leveraging an intensive longitudinal design and data analysis to explore bidirectional daily relations between religious coping and depression symptoms in a community sample of adults with a history of sexual victimization.

Comparison of the effects of production and processing parameters on the eating quality of lamb.

While many separate research studies have investigated the effect of production and processing factors on eating quality of lamb, the relative impact of these parameters has been difficult to ascertain. In this study, the effect of eighteen production and processing factors on the eating quality of Welsh Lamb was compared, using meat from 624 lambs and assessments by 1920 UK consumers. Four experimental trials provided a balanced assessment of production and processing factors: muscle, breed type, lamb gender, ageing, finishing diet, season, carcase hanging and packaging method.

The impact of sports experience on manual dexterity performances in school-age children.

Background: Manual dexterity is the ability to manipulate objects with precision and efficiency, using hands and fingers to achieve a specific objective. This study investigated how the practice of Capoeira, a sport that stimulates coordination skills, affects manual dexterity in children regularly engaged in physical activity or in sedentary children.

Methods: Eighty-four participants were enrolled in this study, including forty-six males and thirty-eight females (age: 8.