Publications by authors named "E K Lacson"

Article Synopsis
  • T cells are essential for fighting tumors and clearing infected cells by recognizing specific targets through T-cell receptors (TCRs) that bind to pMHC molecules on these cells.
  • Current methods for creating pMHC molecules may miss important TCRs that target weaker, yet effective peptides, making personalized immunotherapy challenging.
  • A new method using sortase and click chemistry enables the stable generation of pMHC molecules, improving their binding to TCRs and offering a more effective approach to study and target antigen-specific T cells for cancer treatment.
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Rationale & Objective: Reasons for transfer from peritoneal dialysis (PD) to hemodialysis (HD) remain incompletely understood. Among incident and prevalent patients receiving PD, we evaluated the association of clinical factors, including prior treatment with HD, with PD technique survival.

Study Design: Retrospective cohort study.

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