A placebo-controlled dose response study of the reactogenicity and immunogenicity of a live cold-recombinant influenza B virus vaccine in healthy volunteers.

A live cold-recombinant influenza B virus vaccine (RB77) was given intranasally in a placebo-controlled, double blind study to volunteers in dosages of 10(7.9) EID50/ml, 10(7.25) EID50/ml, 10(5.

[Incidence of hepatitis B virus infection in the medical personnel of physicians' offices].

Serological examination to determine anti-HBc antibodies in 1487 medical personnel working with practitioners in Essen revealed a hepatitis B virus incidence rate of 12.8%. The incidence rate depended on age, years of service, and nature of duties.