Detecting reasons for recurrent deformity in treatment of patients with vitamin D-resistant rickets using diagnostic imaging.

Purpose: To assess age related manifestations of the femur and tibia in patients with vitamin D-resistant rickets (VDR) and explore causes for recurrent deformity using imaging modalities.

Methods: Computed tomography (CT), magnetic resonance imaging (MRI) and dual energy X-ray densitometry (DEXA) were used to assess conditions of long bones of lower limbs in patients with vitamin D-resistant rickets aged from 4 years to 30 years preoperatively and after limb lengthening.

Results: Age related MRI findings showed specific structure of the femur and tibia in patients with VDR preoperatively and after operative treatment.

[Factors influencing the results of chronic glomerulonephritis treatment].

The effectiveness of different treatment programs was studied in correlation with clinical characteristics of chronic glomerulonephritis (CGN) in 665 patients. It was established that the higher was CGN activity, the poorer were the treatment results. Nephrotic syndrome also had negative implications.

[Long-term results of dispensarization of patients with chronic glomerulonephritis].

The results of long-term follow-up (from 4 to 25 years) were studied in 1420 patients with chronic glomerulonephritis registered in the city nephrologic service of Leningrad. The relapses ceased in 45.8% and became less frequent in 16% of cases.

[Experience with the follow-up of patients with chronic glomerulonephritis].

The duration of glomerulonephritis up to the development of azotemia, death or the beginning of programmed hemodialysis was analysed in 605 patients. In 254 of them the term of observation lasted 4-14 years and in 351 patients with a similar characteristic of the disease less than 4 years. The survival rate among the patients with long-term observation was significantly higher than among those who were under observation less time owing to later onset and longer duration of chronic renal insufficiency.