Publications by authors named "E K Akpek"
Objective: There is currently no systematic method of assessing limitations in performing corneal transplantation. The purpose of the study was to identify the limitations of performing corneal transplantation in India.
Design: Cross-sectional survey study.
Purpose: The purpose of this study was to characterize the morphological and immunological aspects of biointegration at the optic-cornea joint of a second-generation synthetic corneal device.
Methods: The initial prototype, single-piece optic-skirt configuration, is constructed from compact and flexible perfluoroalkoxy alkane with porous expanded polytetrafluoroethylene (ePTFE) overlying the skirt to allow skirt-cornea biointegration. The second-generation version was modified to add ePTFE around the optic wall to allow optic-cornea biointegration.
Purpose: This pooled analysis of two pivotal studies (ESSENCE-1 and ESSENCE-2) evaluated treatment effects of a water-free ciclosporin 0.1% solution in dry eye disease (DED) patients in the overall population and in subgroups according to sex, age, and baseline severity of disease.
Methods: In these randomized, multicenter, double-masked, vehicle-controlled studies patients received ciclosporin 0.
Development and Validation of Claims-Based Algorithms for Conjunctivitis and Keratitis.
Pharmacoepidemiol Drug Saf
November 2024
Background: Ocular surface disorders have been reported among patients with various medical conditions, including atopic dermatitis (AD). Nonetheless, validated algorithms to identify conjunctivitis and keratitis in claims data are lacking.
Objective: Develop validated, claims-based algorithms for conjunctivitis and keratitis among patients with AD using medical records.