[Clinical analysis of ofloxacin in treatment of postinfectious exacerbations of endogenous bronchial asthma].

The aim of the study was to analyse the clinical effectiveness of ofloxacin in treatment of post-infectious exacerbations of endogenous bronchial asthma. Twenty eight patients (20 males, 8 females) were assessed. The following parameters were evaluated: bacteriological examination of the sputum (before and after treatment), morphological analysis of peripheral blood, bronchoalveolar lavage (performed in 11 patients).

[Alpha fetoprotein levels in the serum and bronchoalveolar lavage fluid in patients with lung cancer and other diseases of the respiratory system].

Concentration of alpha-fetoprotein (AFP) may be increased in some type of lung cancer. In the study concentration of AFP was evaluated in serum and broncho-alveolar lavage fluid (BALF) in patients with lung cancer. The values of concentration were compared with results obtained from patients with other diseases of the respiratory tract.

[Concentration of carcinoembryonic antigen in the serum and bronchoalveolar lavage fluid in patients with lung cancer].

Serum and BAL CEA levels were determined in stage I (WHO scale) lung cancer patients. The immuno-enzyme assay for the quantitative determination of CEA according to enzyme-linked immunosorbent assay (ELISA) principle was used. Eight smokers without symptoms of respiratory disease served as a control group.

Theophylline in serum and in bronchoalveolar lavage (BAL) in atopic bronchial asthma and chronic bronchitis.

To evaluate the penetration of theophylline into the airways its concentration (Theo-Dur, Astra, Sweden) was determined in BAL and in serum in 20 patients with atopic bronchial asthma, 24 patients with chronic bronchitis and 5 smokers as controls. The results were statistically analyzed. Slow-release theophylline in Theo-Dur was well tolerated.