Publications by authors named "E Jorge-Galarza"
Impact of Lipids and Vascular Damage on Early Atherosclerosis in Adolescents with Parental Premature Coronary Artery Disease.
High Blood Press Cardiovasc Prev
January 2024
Aim: To assess the relationship of cardiovascular risk factors (CRFs) with carotid intima media thickness (IMT) in adolescents with a parental history of premature coronary artery disease (PCAD).
Methods: This cross-sectional study included 50 healthy adolescents, aged 14-18 years, both sexes, with a parental history of PCAD, that were compared to 50 controls without this history. Questionnaires regarding information of CRFs were applied.
Background: High-density lipoproteins (HDLs) have antiatherogenic properties related to their chemical structure. Adipose tissue (AT) influences HDL reverse cholesterol transport and plasma HDL cholesterol levels. However, whether AT dysfunction affects HDL subpopulations and their glycation in early type 2 diabetes (T2D) is still unknown.
View Article and Find Full Text PDFArticle Synopsis
- Plasminogen activator inhibitor 1 (PAI-1) and resistin are linked to metabolic issues related to unhealthy adipose tissue, and the impact of the dietary fatty acids EPA and DHA on this relationship is not well understood.
- A study involving 36 healthy individuals revealed that EPA and DHA were notably associated with resistin and had a marginal connection with PAI-1, influencing glucose metabolism metrics like insulin levels and resistance.
- The findings suggest that EPA and DHA may improve glucose metabolism independently of other metabolic risk factors, indicating their potential role in managing adipose tissue function.
Background: adipose tissue dysfunction is a key factor for diabetes and non-alcoholic fatty liver disease (NAFLD) development. Chia (Salvia hispanica) is an abundant source of omega-3 fatty acids, antioxidants, and fiber which could improve adipose tissue functionality. Aim: to analyze the effect of an isocaloric chia-supplemented diet on glucose metabolism, adipose tissue inflammation, and endothelial function markers in patients with NAFLD and early stages of diabetes.
View Article and Find Full Text PDFEffect of metabolic control on recurrent major adverse cardiovascular events and cardiovascular mortality in patients with premature coronary artery disease: Results of the Genetics of Atherosclerotic Disease study.
Nutr Metab Cardiovasc Dis
September 2022
Background And Aims: Coronary artery disease (CAD) is the leading cause of death around the world, and its rate of presentation is increasing at young ages. Despite the evidence that secondary prevention in CAD reduces the risk of recurrent major adverse cardiovascular events (MACE), no studies have analyzed the composite control of blood pressure, lipids, and glucose control in premature CAD.
Methods And Results: This was a real-world prospective cohort study of patients with premature CAD.