Publications by authors named "E Jaakkola"
Striatal Dopaminergic Function and Motor Slowing in Essential Tremor Plus.
Mov Disord Clin Pract
December 2024
Background: While previous imaging studies have generally shown normal striatal dopamine transporter (DAT) binding in essential tremor (ET), emerging evidence suggests a partial dopaminergic mechanism in this condition and an epidemiological link between ET and Parkinson's disease (PD). This link seems particularly meaningful in ET patients with additional neurological signs, such as slowness of movements, rigidity, or rest tremor (ET+).
Objectives: To investigate the potential dopaminergic pathophysiology of ET+ and to compare it to PD.
Background: Integration of palliative care has been shown to be beneficial and is therefore recommended. However, the specific methods for arranging such care remain unclear. Systematic referral and regular visits with a multi-professional palliative care team have appeared most beneficial.
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- Stuttering affects about 1 in 100 adults, leading to communication issues and social anxiety, often appearing as a developmental disorder but sometimes linked to brain damage.
- The study analyzed three groups: patients with stroke-induced stuttering, a clinical cohort with similar issues, and adults with persistent developmental stuttering, to uncover the brain regions involved.
- Results showed that brain lesions from stuttering are connected to a common network centered around the left putamen, with significant correlations to stuttering impact in participants with developmental stuttering.
Objective: This study was undertaken to investigate the effects of dietary caffeine intake on striatal dopamine function and clinical symptoms in Parkinson disease in a cross-sectional and longitudinal setting.
Methods: One hundred sixty-three early Parkinson disease patients and 40 healthy controls were investigated with [I]FP-CIT single photon emission computed tomography, and striatal dopamine transporter binding was evaluated in association with the level of daily coffee consumption and clinical measures. After a median interval of 6.
Background: Emotions are reflected in bodily sensations, and these reflections are abnormal in psychiatric conditions. However, emotion-related bodily sensations have not been studied in neurological disorders.
Objective: The aim of this study was to investigate whether Parkinson's disease (PD) is associated with altered bodily representations of emotions.