Publications by authors named "E J Will"
Purpose: Visual complaints are a common consequence of acquired brain injury (ABI). Yet, they may be overlooked in clinical practice. The present study aims to develop a screening instrument for assessing visual complaints in individuals with ABI and evaluate its psychometrics properties in a community sample.
View Article and Find Full Text PDFBackground: Restricted and repetitive behaviors (RRBs) are highly prevalent and reduce function in individuals with fragile X syndrome (FXS). As transdiagnostic features of intellectual disability, elevated rates of RRBs in FXS could represent various underlying known co-occurring conditions in FXS such as anxiety or autism spectrum disorder (ASD), yet this distinction has not been investigated. Further, delineating whether RRBs are more indicative of anxiety or ASD in FXS may clarify phenotypic profiles within FXS and improve differential assessment.
View Article and Find Full Text PDFArticle Synopsis
- - Central centrifugal cicatricial alopecia (CCCA) primarily affects Black women and is characterized by scarring that leads to hair loss; conventional treatments focus on inflammation rather than the underlying fibrotic issues.
- - A study was conducted to assess the effects of low-dose oral metformin, an antidiabetic drug with antifibrotic properties, on clinical symptoms and gene expression in CCCA patients unresponsive to standard treatments.
- - Results from 12 participants showed that after at least 6 months of metformin treatment, many experienced symptom improvement and some showed hair regrowth, with gene analysis indicating beneficial changes in pathways related to skin and hair development.
Article Synopsis
- The study focuses on understanding the communication challenges faced by children with the fragile X premutation (FXpm), a genetic variant linked to various health issues in adulthood, particularly social communication difficulties.
- Eighteen children with FXpm, compared to twenty-one typically developing peers, were assessed using standardized language and adaptive communication tests, finding notable delays in social communication among the FXpm group, although they performed similarly in language and adaptive measures.
- The researchers conclude that early identification and intervention for social communication delays in FXpm children could improve their developmental outcomes and suggest that more extensive studies are essential to explore these issues further across different ages and populations.