Publications by authors named "E J Tweedie"
Article Synopsis
- Tricuspid regurgitation (TR) is a common issue after heart transplantation, and a new treatment called transcatheter tricuspid valve replacement (TTVR) has emerged, although it comes with risks.
- A 46-year-old woman who underwent a heart transplant developed severe TR, had a TTVR procedure, but later suffered from cardiogenic shock and sudden cardiac death, linked to complications in the area of her heart's electrical conduction system.
- This case highlights the dangers of TTVR in heart transplant patients, emphasizing the need for close monitoring due to the potential for serious heart rhythm issues like complete heart block.
Extracellular matrix (ECM) remodeling regulates angiogenesis. However, the precise mechanisms by which structural changes in ECM proteins contribute to angiogenesis are not fully understood. Integrins are molecules with the ability to detect compositional and structural changes within the ECM and integrate this information into a network of signaling circuits that coordinate context-dependent cell behavior.
View Article and Find Full Text PDFMutations in endoglin, a TGFβ/BMP coreceptor, are causal for hereditary hemorrhagic telangiectasia (HHT). Endoglin-null (Eng-/-) mouse embryos die at embryonic day (E)10.5-11.
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