Publications by authors named "E J Thacker"
Background: The American Heart Association (AHA), in conjunction with the National Institutes of Health, annually reports the most up-to-date statistics related to heart disease, stroke, and cardiovascular risk factors, including core health behaviors (smoking, physical activity, nutrition, sleep, and obesity) and health factors (cholesterol, blood pressure, glucose control, and metabolic syndrome) that contribute to cardiovascular health. The AHA Heart Disease and Stroke Statistical Update presents the latest data on a range of major clinical heart and circulatory disease conditions (including stroke, brain health, complications of pregnancy, kidney disease, congenital heart disease, rhythm disorders, sudden cardiac arrest, subclinical atherosclerosis, coronary heart disease, cardiomyopathy, heart failure, valvular disease, venous thromboembolism, and peripheral artery disease) and the associated outcomes (including quality of care, procedures, and economic costs).
Methods: The AHA, through its Epidemiology and Prevention Statistics Committee, continuously monitors and evaluates sources of data on heart disease and stroke in the United States and globally to provide the most current information available in the annual Statistical Update with review of published literature through the year before writing.
Frame Running is an adapted community-based exercise option for people with moderate-to-severe walking impairments. This mixed-methods study aimed to examine the feasibility of 1) community-based Frame Running by young people with moderate-to-severe walking impairments and 2) conducting future studies on the impact of Frame Running on functional mobility and cardiometabolic disease risk factors. Weekly training sessions and data collection occurred in two sites.
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- The study investigates the incidence of late onset epilepsy (LOE) among different racial/ethnic groups in the USA, focusing particularly on the Hispanic population, in light of the higher stroke rates in non-Hispanic Blacks (NHBs) and Hispanics compared to non-Hispanic Whites (NHWs).
- It analyzes data from the Northern Manhattan Study, tracking 3,419 participants free from stroke or epilepsy initially over 51,176 person-years, revealing that NHBs have a significantly higher LOE incidence than NHWs, while there was no significant difference between NHWs and Hispanics.
- The findings indicate that the association between incident stroke and the risk of developing LOE is notably stronger in Hispanics (8
Background: Land uses such as crop production, livestock grazing, mining, and urban development have contributed to degradation of drylands worldwide. Loss of big sagebrush (Artemisia tridentata) on disturbed drylands across the western U.S.
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- Bruton's tyrosine kinase inhibitors (BTKis), like acalabrutinib, are the recommended treatment for chronic lymphocytic leukemia (CLL) but can increase the risk of severe infections.
- A 68-year-old male patient developed multiple types of infections, including bacterial, fungal, and viral, while being treated with acalabrutinib.
- This case highlights a potential pattern of increased infection risk associated with BTKis, particularly suggesting that such risks may be a common side effect of the entire medication class.