Publications by authors named "E J Sullivan"

Introduction: Chemoradiotherapy with MRI-guided brachytherapy boosts is the standard of care for locally advanced cervical cancer. Data from the RetroEMBRACE and EMBRACE I trials provide dose-response curves for target volumes and OAR. This study evaluated plan quality, safety and toxicity following escalation of the CTV_HR D90 prescription from 80-90 Gy to 85-95 Gy for two different applicator designs.

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Background: Over a third of children globally do not meet their developmental potential, and children living in low and middle-income countries (LMICs) are most vulnerable. Understanding the contextual factors that influence cognitive development for children in LMICs is crucial to inform and develop interventions. We sought to characterize developmental trajectories of cognition in Bangladeshi children and identify salient social determinants.

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Article Synopsis
  • Adequate nutrition during pregnancy is essential for fetal brain development, and low protein intake can lead to neurological issues in offspring, which is a major global health concern.
  • A study using rhesus macaques showed that reduced maternal protein levels led to structural brain abnormalities and decreased gray matter volume, particularly in areas important for motor control.
  • Although significant brain changes were observed through MRI, early behavioral tests at 1 month showed only minor effects, suggesting that the impacts of protein reduction may not immediately translate to behavior.
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