Publications by authors named "E J Reinhard"
Background & Aims: Hepatocellular carcinoma (HCC) is the third leading cause of cancer-related death. Metabolic dysfunction-associated steatotic liver disease (MASLD) is a significant cause of HCC. Current treatment options for HCC are very limited.
View Article and Find Full Text PDFObjective: To estimate the impact of the UK nationwide campaign to End loneliness on loneliness and mental health outcomes among older people in England.
Design: Quasi-experimental design, namely, a difference-in-differences approach.
Setting: Local authorities across England.
Article Synopsis
- Primary liver cancer, including hepatocellular carcinoma (HCC) and cholangiocarcinoma (CCA), is a leading cause of cancer deaths globally, with limited treatment options available.
- The study investigates the use of a live-attenuated Listeria monocytogenes strain as both a preventive and therapeutic vaccine, showing strong safety and efficacy in mouse models of liver diseases.
- Combining Listeria vaccination with checkpoint inhibitor therapy significantly improved survival rates in mice with advanced HCC, highlighting the potential of this approach for treating liver fibrosis and hepatobiliary cancers.
Background: This study examines the impact of environmental noise policy on depressive symptoms by exploiting the national experiment afforded by the New Deal aircraft noise control policy introduced in Schiphol (Amsterdam) in 2008.
Methods: Data came from older adults (ages 57-102) participating in three waves (2005/2006, 2008/2009 and 2011/2012) of the Longitudinal Aging Study Amsterdam (LASA) (N=1746). Aircraft noise data from the Netherlands Environmental Assessment Agency were linked to LASA cohort addresses using the GeoDMS software.