Publications by authors named "E J Postema"

Animal colour patterns are often accompanied by specific, synergistic behaviours to most effectively defend prey against visual predators. Given the inherent context-dependence of colour perception, understanding how these colour-behaviour synergies function in a species' natural environment is crucial. For example, refuge-building species create a unique visual environment where most (or all) of the body is obscured unless closely inspected.

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Article Synopsis
  • A study was conducted to determine how urinary activity affects the interpretation of F-flotufolastat (F-rhPSMA-7.3) PET/CT scans in prostate cancer patients from two clinical trials, LIGHTHOUSE and SPOTLIGHT.
  • The analysis involved 718 scans evaluated by three certified nuclear medicine physicians, focusing on both qualitative and quantitative assessments of bladder activity and its impact on imaging results.
  • Results showed that 96% of the scans were interpreted as having no or minimal impact from urinary activity, while only a small portion (3.4%) indicated that urinary activity significantly interfered with the assessment, particularly when bladder activity was higher.
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When constraints on antipredator coloration shift over the course of development, it can be advantageous for animals to adopt different color strategies for each life stage. Many caterpillars in the genus exhibit unique ontogenetic color sequences: for example, early instars that masquerade as bird feces, with later instars possessing eyespots. I hypothesize that larvae abandon feces masquerade in favor of eyespots due to ontogenetic changes in signaler size.

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Background: Adverse events identified during clinical trials can be important early indicators of drug safety, but complete and timely data on safety results have historically been difficult to access. The aim was to compare the availability, completeness, and concordance of safety results reported in ClinicalTrials.gov and peer-reviewed publications.

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This study evaluated tracer uptake and lesion detectability with the novel radiopharmaceutical F-radiohybrid (rh)PSMA-7.3 in patients with prostate cancer (PCa). Ten patients (three with high-risk primary localized PCa [Cohort A], three with hormone-sensitive metastatic PCa [Cohort B], and four with castration-resistant metastatic PCa [Cohort C]) underwent whole-body F-rhPSMA-7.

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