Publications by authors named "E J Lopes"

The occurrence of hepatitis E virus (HEV) in patients with Schistosomiasis mansoni (SM) is still poorly understood in Brazil. The objective of this study was to estimate the seroprevalence of anti-HEV IgG in patients with SM and its association with the periportal fibrosis (PPF), assessed by serum markers and ultrasound criteria. This cross-sectional study was carried out in an endemic area in Pernambuco, Brazil, with schistosomal patients who underwent coproscopic survey.

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The study aimed to investigate the influence of different microalgae used in green water culture on the intestinal morphology of the seahorse Hippocampus reidi during the first 15 days of life. Four treatments were tested in triplicate, consisting of two microalgae (Tisochrysis lutea-ISO and Chaetoceros muelleri-CHO), used either individually (TISO and TCHO) or combined (TIC 1:1) in larval rearing water, and a treatment without microalgae (TWM). Larvae (6.

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Background: Women have a higher risk of developing osteoarthritis (OA) than men, including with obesity. To better understand this disparity, we investigated sex differences in metabolic and inflammatory factors associated with OA using a diet-induced mouse model of obesity. We hypothesized that 20 weeks of high-fat diet (HFD) would induce sexually dimorphic changes in both systemic and local risk factors of knee OA.

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Given the capability to produce parts with complex geometries, powder bed fusion using a laser beam (PBF-LB), one of several additive manufacturing techniques, is becoming increasingly prevalent in both research and industry. Advances in the development of biomedical lattice structures show a trend in the use of functional gradients for greater customization and adjustment of mechanical properties according to the demands. This study analyzed four biomedical potential lattice structures (regular and graded) manufactured using PBF-LB in Ti6Al4V alloy.

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Article Synopsis
  • Chromatin structure is crucial for DNA accessibility and gene expression; disrupting it can lead to diseases and cancer.
  • H2B variants, which are slightly different from standard H2B histones, have been found to be dysregulated during processes like epithelial to mesenchymal transition and could function as "oncohistones," similar to other histone mutations linked to cancer.
  • Research indicates that these H2B variants modify chromatin dynamics and can affect oncogenic gene expression, suggesting they could serve as early cancer biomarkers and potential therapeutic targets.
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