Publications by authors named "E J Krull"
Article Synopsis
- During inflammation, increased vascular permeability can lead to harmful effects, especially in inflamed lungs, where microvascular leakage occurs.
- Formylated peptides, which trigger neutrophil activation through FPR1, play a role in regulating this vascular leakage, with research identifying ARAP3 as a protective factor against excessive permeability.
- Studies showed that ARAP3 deficiency in endothelial and immune cells led to increased microvascular leakage and neutrophil activity, hinting at its significance in conditions with high levels of formylated peptides, such as severe influenza.
Article Synopsis
- Researchers are studying a type of surgery called vNOTES to see if it affects women's sexual function after they have surgery for certain health problems.
- They will compare vNOTES with another surgery method called CAL to see if there's any difference in how women feel after their operations.
- The study will include women aged 18-70 years, and they'll fill out surveys about their sexual health before and after the surgery.
Off-label drug use is common practice in palliative care. It may pose a risk to the patient and benefit should outweigh harm. A decision and documentation aid for off-label use was developed to support practitioners in clinical practice off-label use.
View Article and Find Full Text PDFThe German Association of Palliative Care developed an evidence-based guideline about the management of malignant wounds in adult patients with incurable cancer. There is a lack of evidence-based guidelines about fungating wounds and a confusing wide range of available wound dressings. The goal of the guideline is to reduce the suffering of patients with malignant wounds and stabilize or improve their quality of life.
View Article and Find Full Text PDFArticle Synopsis
- A case of congenital toxoplasmosis (TXP) is presented in a woman who had a Toxoplasma gondii infection over 6 months prior to conception and was treated with adalimumab for ankylosing spondylitis.
- Serology tests during her first trimester indicated prior infection, and an ultrasound at 26 weeks revealed cerebral lesions suggesting intrauterine infection.
- Following amniocentesis confirming TXP, the pregnancy was terminated at the parents' request, and the diagnosis was validated through fetal autopsy, highlighting concerns about immunosuppressive treatments like adalimumab and the necessity of preconception counseling.