Publications by authors named "E J Kroot"
PERFECTRA: a pragmatic, multicentre, real-life study comparing treat-to-target strategies with baricitinib versus TNF inhibitors in patients with active rheumatoid arthritis after failure on csDMARDs.
Celine J van de Laar Martijn A H Oude Voshaar Peter Ten Klooster Danyta I Tedjo Reinhard Bos Eric-Jan Kroot
RMD Open
May 2024
Article Synopsis
- The study compares the effectiveness of baricitinib and TNF-inhibitors (TNFi) in treating rheumatoid arthritis (RA) patients who did not respond to conventional treatments.
- A total of 199 patients were randomized, showing baricitinib to be both non-inferior and superior in achieving meaningful clinical responses at 12 weeks, with a higher percentage of patients reaching specified disease activity targets compared to TNFi.
- The results suggest that baricitinib may be a more effective initial treatment option than TNFi for RA patients who have failed previous therapies, based on the outcomes measured over 48 weeks.
Physical activity and body composition in patients with ankylosing spondylitis.
Arthritis Care Res (Hoboken)
January 2012
Objective: Patients with ankylosing spondylitis (AS) are at risk for accelerated muscle loss and reduced physical activity. Accurate data are needed on body composition and physical activity in this patient group. The purpose of this study was to investigate body composition and objectively assessed physical activity in patients with AS.
View Article and Find Full Text PDFEosinophilic fasciitis (EF) is a disease with unknown aetiology, although an immunologic pathogenesis is suspected. The characteristic features of this inflammatory disease include scleroderma-like skin indurations, predominantly on the extremities, and peripheral blood eosinophilia. Internal organs are generally not affected.
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