Publications by authors named "E J KAO"

Reporting by major media outlets influences news coverage by other outlets, resulting in an outsized impact on public opinion. Understanding this inter-outlet influence, known as intermedia agenda setting, is important for assessing the impact of state media and strategic communications. We demonstrate a novel method to quantify inter-outlet influence using causal inference on "quote following," where one outlet uses the same quote as another outlet at a later date.

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Immune checkpoint inhibitors (ICI) have revolutionized cancer therapy, but their use is limited by the development of autoimmunity in healthy tissues as a side effect of treatment. Such immune-related adverse events (IrAE) contribute to hospitalizations, cancer treatment interruption and even premature death. ICI-induced autoimmune diabetes mellitus (ICI-T1DM) is a life-threatening IrAE that presents with rapid pancreatic beta-islet cell destruction leading to hyperglycemia and life-long insulin dependence.

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Article Synopsis
  • - The study explores the use of therapeutic limb hypothermia to reduce tissue injury during traumatic limb ischemia, focusing on its effects during damage control resuscitation in a swine model.
  • - Fifteen swine were subjected to a 6-hour resuscitation protocol, with one hindlimb cooled to either 5°C or 15°C, while the other limb remained uncooled for comparison; various physiological and tissue measurements were taken during this time.
  • - Results showed that cooling to 15°C lowered harmful metabolites in the tissues without increasing damage, while cooling to 5°C led to more muscle damage, suggesting that local hypothermia can help prevent ischemic injury but needs further study.
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Differential dynamic microscopy (DDM) typically relies on movies containing hundreds or thousands of frames to accurately quantify motion in soft matter systems. Using movies much shorter in duration produces noisier and less accurate results. This limits the applicability of DDM to situations where the dynamics are stationary over extended times.

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Case: This case demonstrates a 2-year-old boy with a rare benign supraclavicular mass diagnosed as neuromuscular choristoma through open biopsy. Postoperatively, he underwent semiannual surveillance with ultrasound without development of neurological complaints, limb deformity, or recurrence at 2-year follow-up.

Conclusion: Neuromuscular choristoma involving the brachial plexus is a rare tumor that should be in the differential diagnosis of pediatric peripheral nerve-based tumors.

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