Publications by authors named "E J Herman"
Article Synopsis
- The study focuses on the early detection and intervention of unilateral cerebral palsy (UCP) in infants to enhance long-term motor skills through a specific therapy called HABIT-ILE.
- Conducted as a randomized clinical trial in Brussels, Belgium, infants aged 6 to 18 months were paired by age and lesion type and assigned to either a treatment group receiving intensive therapy or a control group maintaining usual activities.
- The effectiveness of the therapy was assessed through various motor function metrics, with the primary measurement being the use of the more affected hand, alongside additional evaluations like the Canadian Occupational Performance Measure and Gross Motor Function Measure scores.
Out with the old, in with the new? Institutional experimentation and decent work in the UK.
Econ Ind Democr
November 2024
Drawing on an extended critical case study of the Greater Manchester (GM) city region in the UK, this article contributes to debates around the changing role of social actors within local labour markets, and how they contribute to processes of regulatory experimentation and innovation. While recent literature has drawn attention to new actors and novel strategies in responding to labour market disruptions, in this article the authors argue that there is still room for embedded actors and established practices in defending, and advancing, decent minimum standards. This may be through political lobbying, workplace organising, industrial action, extending collectively agreed standards to outsourced workers, or through hybrid forms of trade union-community campaigning.
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- The study investigates which polygenic scores (PGSs) for coronary artery disease (CAD) are most effective in identifying high-risk individuals within the Italian population, highlighting the need for tailored genetic risk assessment tools.
- Using data from two independent Italian cohorts, the researchers analyzed 266 PGSs and found that 49 of them showed significantly different distributions between CAD patients and controls, with PGS003727 being the most accurate.
- The findings suggest that existing European CAD PGSs may not be uniformly applicable across different populations, emphasizing the importance of further validation for clinical use in specific regions like Italy.
Article Synopsis
- Paramyxoviruses, such as measles and Nipah, pose significant public health risks and have pandemic potential, with HPIV3 being a major cause of illness among vulnerable populations.
- * There are currently no approved vaccines or treatments for HPIV3, but neutralizing monoclonal antibodies (mAbs) could be a promising strategy despite challenges from viral resistance due to mutations.
- * The study presents cryo-electron tomography structures showing how mutated HPIV3 can evade neutralization by mAbs by altering the interaction between viral proteins, providing insights that could inform future mAb design.
Effectiveness of Changing Drug Classes in Patients With Refractory Laryngopharyngeal Reflux Disease.
Otolaryngol Head Neck Surg
September 2024
Objective: To investigate the effectiveness of drug class changes in patients with refractory laryngopharyngeal reflux disease (LPRD).
Study Design: Retrospective case series with prospective data.
Setting: Multicenter study.