Publications by authors named "E J Fitzsimons"

Article Synopsis
  • The study aims to enhance the UK Millennium Cohort Study by linking it with street-level crime data to assess the impact of local crime on participants' experiences and perceptions of safety.
  • Using police data from a span of eight years, the researchers created individual-level crime measures for 11,365 participants, focusing on crime counts and rates surrounding their homes at different ages.
  • Results showed stable overall crime rates, but notable fluctuations in specific crime types, particularly an increase in violent and sexual offences, as well as an observed negative relationship between household income and exposure to neighborhood crime.
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Tumor-infiltrating B cells play a significant role in tumor development, progression, and prognosis, yet a comprehensive classification system is lacking. To address this gap, we present a pan-cancer single-cell RNA sequencing (scRNA-seq) atlas of tumor-infiltrating B and plasma cells across a large sample cohort. We identify key B cell subset signatures, revealing distinct subpopulations and highlighting the heterogeneity and functional diversity of these cells in the tumor microenvironment.

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Article Synopsis
  • Minimizing questionnaire length is crucial in research on eating disorders to enhance engagement and reduce the burden on participants, especially regarding sensitive topics that may evoke negative emotions.
  • The study employed item response theory to shorten three established scales related to eating disorders while maintaining their original measurement quality, assessing the reliability and validity of these new shorter forms.
  • Findings revealed successful shorter versions of the Eating Disorder Examination Questionnaire, the SCOFF questionnaire, and the Dysmorphic Concern Questionnaire, showing good fit and valid correlations with longer versions and other relevant measures among UK adults.
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Decades of research shows that sexual minority youth (SMY) display heightened risk for mental health problems, although the onset of such disparities remains unclear. The Millennium Cohort Study is the largest nationally representative longitudinal study of adolescents in the United Kingdom. In this study, participants ( = 10,047, 50% female) self-reported their sexual identity at age 17 and had parent-reported mental health data, from the Strengths and Difficulties Questionnaire, reported across five waves at ages 5, 7, 11, 14, and 17.

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Article Synopsis
  • The study examines how living near fast food restaurants affects weight gain in children from ages 7 to 14, using data from the UK Millennium Cohort Study.
  • Results show that children with mothers who have less than a degree are more likely to gain weight if they live close to these outlets.
  • Additionally, children with lower emotional regulation skills face a higher risk of increased weight in this context.
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