Kisspeptin as a test of hypothalamic dysfunction in pubertal and reproductive disorders.

The hypothalamic-pituitary-gonadal axis is regulated by the gonadotropin-releasing hormone pulse generator in the hypothalamus. This is comprised of neurons that secrete kisspeptin in a pulsatile manner to stimulate the release of GnRH, and, in turn, downstream gonadotropins from the pituitary gland, and subsequently sex steroids and gametogenesis from the gonads. Many reproductive disorders in both males and females are characterized by hypothalamic dysfunction, including functional disorders (such as age-related hypogonadism, obesity-related secondary hypogonadism, hyperprolactinemia, functional hypothalamic amenorrhea and polycystic ovary syndrome), structural pathologies (such as craniopharyngiomas or radiation or surgery-related hypothalamic dysfunction), and pubertal disorders (constitutional delay of growth and puberty and congenital hypogonadotropic hypogonadism).

Bridging theory and practice: Experiences of diagnostic radiography students during clinical training in resource-constrained settings.

Introduction: Clinical training is crucial for diagnostic radiography students, bridging theoretical knowledge with practical skills. In resource-constrained settings, this training may face unique challenges that might significantly impact learning outcomes and future practice. Despite its importance, the experiences of diagnostic radiography students during clinical placements remain understudied, particularly in Sub-Saharan Africa.

Examining Relations Between Sexualizing Media Exposure and Sexting Attitudes and Behaviors among U.S. Adolescents.

Based on social cognitive processes (Bandura, 2009), sexualizing media likely provide adolescents with credible role models for their own sexualized self-presentation in other mediated contexts, such as sexting. A survey of 6,093 US adolescents was conducted (Mage = 15.27 years, SD = 1.

Unmet needs for long-term services and supports and associations with health outcomes.

Background: The availability of population-level data on unmet needs for long-term services and supports (LTSS) is limited at state and national levels. Data on unmet LTSS needs can improve our understanding of disparities and relationships with health outcomes.

Objective: 1) Explore differences in unmet LTSS needs by socio-demographic characteristics, including age, sex, race/ethnicity, metropolitan status, sexual orientation, and socio-economic status; and 2) Examine associations between unmet LTSS needs and health/preventative healthcare outcomes.