Publications by authors named "E J Costello"
Bone mineral density (BMD), an important marker of bone health, is regulated by a complex interaction of proteins. Plasma proteomic analyses can contribute to identification of proteins associated with changes in BMD. This may be especially informative in stages of bone accrual and peak BMD achievement (i.
View Article and Find Full Text PDFEnteropathogenic Escherichia coli (EPEC) is a gastrointestinal pathogen that affects individuals of all age groups, with infections ranging from subclinical colonization to acute or persistent diarrhea. The bacterium's ability to cause diarrhea depends on the locus of enterocyte effacement (LEE) pathogenicity island. Although regulation of the LEE has been systematically characterized, until the last decade, studies mainly focused on its transcriptional control.
View Article and Find Full Text PDFBackground: The world has experienced devastating extreme weather events, alongside slow-onset processes including increasing temperature means, that scientists agree are manifestations of human-induced climate change. Even with radical action to reduce greenhouse gas emissions, effects of climate change will become increasingly severe.
Objectives: The aim of this review was to classify impacts of climate change for people who use alcohol and other drugs (AoD), as reflected in peer reviewed literature.
Article Synopsis
- Most people in the US are exposed to PFAS, which can lead to health risks, especially in low-income communities near PFAS-polluting facilities.
- In a study in Southern California, researchers connected PFAS levels in plasma samples with data on water contamination, food access, and pollution sources to analyze exposure impacts.
- Results showed that higher PFAS levels in drinking water and the presence of Superfund sites increased PFAS concentrations in participants' blood, highlighting the need to address PFAS exposure in disadvantaged areas.
Background: Per-and polyfluoroalkyl substances (PFAS) contamination may disrupt sleep through disrupted metabolic and immune functions. The study aims to investigate the association and potential mechanism between PFAS and sleep.
Methods: We included 136 young adults recruited between 2014-2018 and 76 were re-assessed between 2020-2022.