Hip dislocation in spastic cerebral palsy: long-term consequences.

We evaluated 38 noninstitutionalized patients with spastic quadriplegic cerebral palsy with 51 dislocated hips. Nine hips had been reduced. The mean follow-up was 18 years, with an average age of 26 years.

The search for the primary tumor in patients with skeletal metastases of unknown origin.

Forty-six patients who had been evaluated because of skeletal metastases of unknown origin, were reviewed. Twenty-six of the patients were referred to an orthopedic surgeon before confirmation of the metastases by biopsy; 20 others were referred to an oncology clinic after a diagnosis of bone metastases had been established. A simple diagnostic sequence consisting of a medical history, physical examination, routine laboratory studies, chest roentgenogram, technetium 99m phosphonate bone scintigram, and intravenous pyelogram identified the site of the primary tumor in 14 patients; 7 of the primaries were lung carcinomas, 4 were hypernephromas, 2 were breast carcinomas, and 1 was a prostate carcinoma.

The effect of adjunctive methylmethacrylate on failures of fixation and function in patients with intertrochanteric fractures and osteoporosis.

In a retrospective review of eighty-two intertrochanteric fractures (twenty-nine stable and fifty-three unstable) in seventy-nine elderly, debilitated patients with associated advanced osteoporosis (Grade III or less by the system of Singh et al.), fifty-six were available for follow-up: twenty-eight that had been treated at the University of Illinois with an approximately anatomical reduction and compression-screw fixation and twenty-eight (in twenty-seven patients) that had been treated at the University of Chicago with an approximately anatomical reduction, compression-screw fixation, and adjunctive methylmethacrylate bone cement in the head-neck fragment. Follow-up analysis after an average of thirty-four months for the group that had augmentation with cement and an average of twenty-six months for the uncemented group showed that for the eighteen stable fractures that could be followed the rates of complications of fixation were the same in the two groups, while for the thirty-eight unstable comminuted fractures that were followed the rate of complications of fixation was lower when adjunctive methylmethacrylate cement was used.

Arterial foam cells with distinctive immunomorphologic and histochemical features of macrophages.

A variable population of fat-filled "foam" cells in diet-induced experimental arterial intimal plaques of rabbits and monkeys were analyzed for several features characteristic of macrophages. These included: 1) surface binding and phagocytosis of antibody-coated or complement-coated erythrocytes to detect specific surface receptors; 2) cytochemical tests and ultrastructural features to evaluate cell function and structure; and 3) rapid adherence to glass, a feature of macrophage activity, to isolate and identify a homogeneous population of fat-filled foam cells from excised and disrupted arterial lesions. Mixed populations of cells grown in culture from explants of lesions were also analyzed and lipid-filled cells were studied in histologic sections of adjacent lesions.