Publications by authors named "E J A Roldan"
Background: Huanglongbing (HLB) is a systemic disease of citrus caused by the bacterial pathogen Candidatus Liberibacter asiaticus (CLas) that limits citrus production worldwide. CLas is an obligate bacterial pathogen that multiplies in citrus trees and in the insect vector, the Asian citrus psyllid (ACP), Diaphorina citri Kuwayama. There is no cure for HLB currently and broad-spectrum antibiotics represent one possible therapeutic against disease symptoms.
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- Protamines are proteins vital for sperm chromatin condensation, with their expression ratios linked to fertility in different species.
- The study aimed to evaluate RNA quality and protamine gene expression in testis samples from wild-derived mice, preserved under various conditions over different time frames.
- Results indicated that samples preserved in RNAlater® or NAP buffer at -80°C maintained RNA integrity and protamine expression effectively, even under less optimal conditions like room temperature for a week.
Is stochastic thermodynamics the key to understanding the energy costs of computation?
Proc Natl Acad Sci U S A
November 2024
Article Synopsis
- The relationship between thermodynamics and computation has fascinated scientists since the 19th century, but its significance has grown due to the rising energy costs of digital devices.
- Real-world computers, including biological ones like brains, operate under various physical constraints, which impact their thermodynamic dynamics and efficiency.
- The emerging field of stochastic thermodynamics offers new analytical techniques to explore how these constraints affect the fundamental thermodynamic properties of systems performing computation.
Effect of Probiotics on Sperm Quality in the Adult Mouse.
Ana Sanchez-Rodriguez Ingrid I D Idrovo Rocío Villafranca Nerea Latorre Juan Antonio Rielo Eduardo R S Roldan
Probiotics Antimicrob Proteins
October 2024
Article Synopsis
- Probiotics have recently gained attention for their potential therapeutic effects, but their impact on reproductive health remains under-researched.
- This study tested the effects of two probiotic mixtures on sperm quality in mice, comparing them to a control group that received physiological serum.
- Results indicated that probiotic treatments resulted in a higher percentage of normal sperm and altered head shape, although they didn't significantly improve overall motility compared to controls, suggesting further research is needed.