Publications by authors named "E Izal- Linares"

Article Synopsis
  • Sperm small RNAs, particularly tRNA fragments (tRFs), are influenced by environmental factors and play a role in passing down paternal traits.
  • The study examines the impact of four specific ribonuclease genes (Rnase9-12) on sperm fertility and small RNA levels by creating knockout (KO) mice that lack these genes.
  • KO male mice were found to be sterile, with notably low levels of tRFs in their sperm, revealing the importance of these genes in sperm development and function.
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Article Synopsis
  • * Researchers investigated the role of four paralogs of Angiogenin, which are expressed in the epididymis, by creating mice that lacked these genes; the results showed that these genes are critical for male fertility and RNA processing.
  • * The KO mice were completely sterile, with their sperm unable to successfully fertilize oocytes due to impaired passage through the reproductive tract and a notable decrease in levels of tRFs, indicating these Angiogenin paralogs are vital for regulating sperm RNA composition.
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Background: Latine people, comprising 18.5% of the US population, constitute the largest ethnic minority group, with nearly one-third self-identifying as having non-English language preference (NELP). Despite the importance of the telephone in health care access, there is limited understanding of how NELP patients navigate telephone calls with primary and specialty care clinics.

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