[Fibrinolysis system in patients with sepsis in state of myelotoxic agranulocytosis].

Purpose: Hemostasis disorders are the part of multiple organ failure (mOF) in sepsis. This work objective is to evaluate the system parameters in septic patients.

Patients And Methods: 55 oncohaematological patients were included in study: 45 with sepsis and 10 patients in control group (no signs of infection).

[Approbation of a new test system determining the activity of a plasmin inhibitor in patients with sepsis].

Plasmin inhibitor (PI) determination is an essential diagnostic method. The purpose of the study was to develop an amidolytic assay for estimating PI activity, by applying the test system made by RENAM (Moscow). The new system is based on purified plasmin (human plasma) with the activity attested by the international standards.