Publications by authors named "E Inci Coskun"
The purpose of this review is to serve as an update on congenital cytomegalovirus (CMV) evaluation and management for obstetrician-gynecologists and to provide a framework for counseling birthing people at risk for or diagnosed with a primary CMV infection or reactivation or reinfection during pregnancy. A DNA virus, CMV is the most common congenital viral infection and the most common cause of nongenetic childhood hearing loss in the United States. The risk of congenital CMV infection from transplacental viral transfer depends on the gestational age at the time of maternal infection and whether the infection is primary or nonprimary.
View Article and Find Full Text PDFParkinson's disease is primarily marked by mitochondrial dysfunction and metabolic abnormalities. We recently reported that the combined metabolic activators improved the immunohistochemical parameters and behavioural functions in Parkinson's disease and Alzheimer's disease animal models and the cognitive functions in Alzheimer's disease patients. These metabolic activators serve as the precursors of nicotinamide adenine dinucleotide and glutathione, and they can be used to activate mitochondrial metabolism and eventually treat mitochondrial dysfunction.
View Article and Find Full Text PDFArticle Synopsis
- The study investigates the levels of Vascular Peroxidase 1 (VPO1), humanin, and MOTS-c in untreated preeclamptic pregnancies, focusing on their relationship with miR-200c expression and comparing these findings to endoglin levels.
- Blood samples from preeclamptic patients showed significantly elevated levels of endoglin, VPO1, and miR-200c, while MOTS-c levels were reduced; humanin levels did not differ significantly.
- A strong positive correlation was found between endoglin and VPO1, suggesting that these molecular changes may play a role in the pathogenesis of preeclampsia and contribute to endothelial dysfunction.
Aim: This prospective, randomized, observational study aimed to compare the efficacy of intrauterine lidocaine, oral dexketoprofen, cervical lidocaine spray, and paracervical block with prilocaine for pain management during outpatient endometrial biopsy (EMB).
Methods: One hundred ninety-seven women aged 18-75 undergoing EMB were randomly assigned to one of four groups: intrauterine lidocaine (n = 49), oral dexketoprofen (n = 48), cervical lidocaine spray (n = 50), or paracervical block with prilocaine (n = 50). Pain intensity was assessed using a visual analog scale (VAS) immediately post-procedure and at 30 min, with additional analgesia needs recorded at 60 min.
Article Synopsis
- The study aimed to understand the needs and expectations of individuals with spinal cord injuries (SCI) requiring long-term rehabilitation at a hospital in Türkiye.
- Conducted with 120 participants through a survey, it found that robotic rehabilitation and psychological support were top priorities, while interest in sexual rehabilitation was lower.
- The results highlight the demand for specialized SCI services and emphasize the importance of addressing sexual rehabilitation in future care strategies.