[Immunological analysis of the surface components of the influenza virus similar to the serovariant A (Hsw1N1) isolated in Alma-Ata 1984-1985].

The results of immunological analysis of the antigenic structure of hemagglutinin and neuraminidase of influenza A (serovariant Hsw 1) isolates recovered in Alma-Ata in 1984-1985 are presented. By means of specific adsorption and immunoprecipitation the antigenic structure of new isolates was shown to be very similar to that of the A/swine/Iowa/15/30 strain.

[Formation of mixed hemagglutinin trimers during double infection with influenza virus strains of the same subtype].

Formation of hemagglutinin spikes in the course of the mixed infection of cell culture by two influenza virus strains belonging to the same antigenic subtype or to different subtypes was studied by means of immunoprecipitation of [14C]-labelled hemagglutinins from cell lysates. The immunoprecipitates were further analysed by polyacrylamide gel electrophoresis. Lysates of separately infected cells mixed before lysis were used as control samples.

[Infectivity of influenza viruses for an organ culture of human embryonic trachea and the change in this trait in recombination].

The infecting and reproduction activity of epidemic and vaccine strains of influenza virus as well as their recombinants was studied in human embryo trachea culture. At a certain combination of genes the recombinants showed new qualities: increased tropism to cells of the human upper respiratory tract and intensified virus reproduction in these cells. Of special interest was a recombinant containing the inner proteins of A/Leningrad/9/46 (H0N1) virus and external proteins of A/Brazil/11/78 (H1N1) virus.