Publications by authors named "E I Shalaby-Rana"

Article Synopsis
  • This study examines hydronephrosis in the lower part of duplex kidneys, using a technique called MAG-3 diuresis renography to assess its prevalence and behavior compared to single-system kidney obstructions.* -
  • Researchers analyzed over 5000 diuresis renograms and identified 19 affected renal units in 18 patients, noting that many cases were diagnosed before birth and showed varied drainage patterns during follow-up.* -
  • The findings suggest that hydronephrosis in duplex systems is uncommon but similar in behavior to obstructions in single kidneys, highlighting the importance of diuresis renography in diagnosis and treatment.*
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MicroRNAs (miRNAs), short, highly conserved non-coding RNA, influence gene expression by sequential mechanisms such as mRNA breakdown or translational repression. Many biological processes depend on these regulating substances, thus changes in their expression have an impact on the maintenance of cellular homeostasis and result in the emergence of a variety of diseases. Relevant studies have shown in recent years that miRNAs are involved in many stages of bone development and growth.

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Article Synopsis
  • Hydronephrosis from UPJ obstruction is common in infants with prenatal diagnosis, leading to surgeries like pyeloplasty due to drainage issues or kidney function decline, but the natural history of cases with non-obstructive drainage and reduced renal function is not well understood.
  • The study analyzed data from patients with significant hydronephrosis and low differential renal function, observing them over time to determine how many experienced worsening kidney drainage or function decline.
  • Out of 29 patients studied over an average of 2.8 years, nearly half showed worsening drainage, with some requiring surgery, while a few managed to improve without obstructive patterns.
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Despite evidence supporting the specificity of classic metaphyseal lesions (CML) for the diagnosis of child abuse, some medicolegal practitioners claim that CML result from rickets rather than trauma. The purpose of this study was to evaluate radiologists' diagnostic performance in differentiating rickets and CML on radiographs. This retrospective seven-center study included children younger than 2 years who underwent knee radiography from January 2007 to December 2018 and who had either rickets (25-hydroxyvitamin D level < 20 ng/mL and abnormal knee radiographs) or knee CML and a diagnosis of child abuse from a child abuse pediatrician.

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Introduction And Objective: Prior studies have shown a broad half time (T1/2) interval on MAG3 diuresis renography (DR) that is indeterminate for obstruction. We aimed to refine and sub-divide the indeterminate range and associate it with clinically meaningful outcomes: pyeloplasty and pyeloplasty-free survival.

Methods: We identified patients <1.

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