Publications by authors named "E I Lupu"
Motor skill development is crucial in human growth, evolving with the maturation of the nervous and musculoskeletal systems. Quantifying these skills, especially coordinative abilities, remains challenging. This study aimed to assess the performance of five motor tasks in children and adolescents using high-speed video analysis, providing data for movement and health professionals.
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- The COVID-19 pandemic, caused by SARS-CoV-2, has resulted in over seven million deaths globally, prompting the development of the BriLife vaccine by the Israel Institute for Biological Research.
- BriLife is based on a modified vesicular stomatitis virus that expresses the spike protein of SARS-CoV-2 to enhance immune response.
- A newly validated plaque assay using Vero E6 cells showed high reliability in measuring the vaccine's viral vector concentration, proving to be accurate and robust across different preparations.
This state-of-the-art review explores the emerging field of regenerative hydrogels and their profound impact on the treatment of skin wounds. Regenerative hydrogels, composed mainly of water-absorbing polymers, have garnered attention in wound healing, particularly for skin wounds. Their unique properties make them well suited for tissue regeneration.
View Article and Find Full Text PDFEnhanced production yields of rVSV-SARS-CoV-2 vaccine using Fibra-Cel macrocarriers.
Front Bioeng Biotechnol
February 2024
The COVID-19 pandemic has led to high global demand for vaccines to safeguard public health. To that end, our institute has developed a recombinant viral vector vaccine utilizing a modified vesicular stomatitis virus (VSV) construct, wherein the G protein of VSV is replaced with the spike protein of SARS-CoV-2 (rVSV-ΔG-spike). Previous studies have demonstrated the production of a VSV-based vaccine in Vero cells adsorbed on Cytodex 1 microcarriers or in suspension.
View Article and Find Full Text PDFBackground: Diet and lifestyle play important roles in preventing and improving chronic diseases, and evaluating behavioral risk factors in these pathologies allows for efficient management.
Methods: A clinical study by screening biochemical parameters and pulmonary function was carried out to evaluate behavioral risk factors in obstructive pulmonary disease associated with metabolic syndrome.
Results: Of the total of 70 patients included in the clinical study, 46 were men and 24 were women (χ = 3.