[C-reactive protein as possible early prognostic marker of restenosis development in coronary artery stents].

Aim: To study possible link between inflammatory response of the body to stent implantation and development of instent restenosis.

Methods: C-reactive protein (CRP) was determined in 24 patients subjected to coronary stenting. Coronary angiography was repeated in 7.

[Role of coronary collateral circulation in the compensation of disorders of myocardial perfusion and left ventricular function in patients with newly appearing angina pectoris].

The myocardial perfusion and left ventricular function were evaluated by bicycle ergometry and myocardial scintigraphy in 23 patients with primary angina taking into account the status of coronary collateral circulation in response to stenotic and occlusive atherosclerosis. In addition to severe occlusive disease of the coronary bed, most patients had significant disturbances of myocardial perfusion and left ventricular function, which were detected during exercise tests. In patients with compensatory collateral circulation in the coronary bed, such disturbances were less marked than in those without anastomoses.

[Metabolic and structural characteristics of myocardial mitochondria in patient with acquired heart defects, operated on under conditions of artificial circulation].

Considering the significance of the unity distinguishing the level of aerobic energy generation in the myocardium, the morphological integrity of the mitochondrial membranes and the regulating influence exercised upon them by the hormones and mediators of the sympathoadrenal system the authors undertook a synchronous study of these factors in patients with rheumatic heart diseases when subjected to the cardiac valves prosthetics. These factors were found to play a key role in ensuring the contractility of the myocardium, this being confirmed by the results of clinico-biochemical comparisons. In a group of patients with dissociated processes of oxidative phosphorylation and a well-marked disintegration of membranous mitochondrial structures, as well as with a low adrenalin, noradrenaline and their precursors level in the myocardium, almost as a rule, in the early post-operative period there appeared symptoms of cardiac incompetence.