[A difference in the growth-controlling action of Syrian hamster fibroblasts from early and late embryogenesis on tumor cells with different degrees of malignancy].

The difference in the effect of embryo fibroblasts from early (EHEF) and late (LHEF) embryos on the proliferative activity (PA) of transformed and tumour cells of different degree of malignancy was demonstrated in culture. The dense monolayer of EHEF cells exerted stronger growth-inhibitory influence on the PA of all tested strains of the transformed and tumour cells as compared to the LHEF cells.

[Suppression and activation of proliferative activity of tumor cells of varying degree of malignancy in contact with normal embryonic fibroblasts of Syrian hamster].

The proliferative activity (PA) of in vitro transformed embryo fibroblasts of syrian hamsters and their in vivo selected variants of the different degree of malignancy in the close contact with irradiated normal embryo fibroblasts of Syrian hamster (HEF) has been examined. The obtained data demonstrate that PA of the STHE and it's low malignant variants were considerably inhibited in contact with the normal fibroblasts and this effect was retained or even augmented from the 1st to the 6th days of the experiment. More malignant variant of the STHE STHE-MLN-6 was inhibited by HEF to the less degree, the inhibitory effect was decreasing during the experiment and disappeared to the 6th day.

[Screening of sera from the adult populations of some USSR regions for antibodies to the human T-cell leukemia virus type I (HTLV-I)].

The results of serologic survey of 4118 residents of the USSR Far East from 16 to 82 years of age and 1037 blood donors for antibody to HTLV-I by the method of passive agglutination of gelatin particles coated with viral proteins are summarized. The portion of HTLV-1 seropositive subjects in the Khabarovsk Territory was 1.79% (25 out of 1391), in the Maritime Territory 2.