[The case of completed pregnancy of the patient with Dandy-Walker malformation].

Dandy-Walker malformation is a rare disease of the central nervous system pathology (congenital malformations of the fossa cranii posterior). The key features of this syndrome are an enlargement of the fourth ventricle; complete absence of the cerebellar vermis, the posterior midline area of cerebellar cortex responsible for coordination of the axial musculature; and cyst formation near the internal base of the skull. Pregnant patients with Dandy-Walker malformation are at high risk and are managed by multidisciplinary teams including neurologists and obstetricians.

[The case of completed pregnancy after hemorrhagic stroke in the patient with moyamoya disease].

Moya-moya syndrome is a rare chronic genetic disease characterized by progressive cerebral vascular occlusion and progressive stenosis of inner carotid arteries resulting in the frequent ischemic attacks and development of collateral arterial circulation. Pregnant patients with moya-moya syndrome are at high risk due to the development of complications. The authors present a case report of full-term pregnancy in a woman with moya-moya syndrome.

[The characteristics of probiotic properties of strains of genus of bifidobacterium separated from gastrointestinal tract of residents of the central region of Russia].

The 156 samples of feces separated from healthy residents of the Central region of Russia were used to compose collection of 87 strains of Bifidobacterium out of which 5 strains with wide antagonistic activity related to pathogenic and opportunistic microorganisms were selected. The selected strains are characterized by high probiotic potentials. They have adhesive properties and sensitivity to antibiotics and preparations corresponding to main requirements of common pharmacopoeia articles to strains of microorganisms used in production of probiotics for medicinal application.

[Antagonism of lactobacilli, oral streptococci and staphylococci].

From the oral cavity of healthy young people aged 18-22 years there were isolated 26 strains of lactobacilli, 28 streptococci, including the pathogenic and opportunistic strains, and 32 strains of staphylococci, 10 of which were methicillin-resistant S.aureus. Oral lactobacilli possessed by a high probiotic potential, showing high antagonism to methicillin-resistant staphylococci, pathogenic and opportunistic streptococci and enterococci.

[Effect of diazoxide on the AS-30D rat ascites hepatoma cells treated by Cd2+].

For the last years, in several investigations, including ours, it was shown that oxidative stress and mitochondrial dysfunction mediated by disturbance of the mitochondrial respiratory chain and by induction of Ca2+ -dependent nonselective high-conductance pore of the inner mitochondrial membrane are involved in mechanism(s) of cytotoxic action of heavy metals. At the same time, possible interaction of heavy metals with other channels, in particular, with selective potassium channels, such as ATP-dependent potassium channels, which are generally considered to be protective for the cells, have not been studied. The aim of the present work was to examine the effect of diazoxide, an activator of mitochondrial ATP-dependent potassium channels, on mitochondrial physiology and cell survival in the presence of Cd2+.