[Proliferative activity of human endothelial cell line EA.hy926 and its modulation].

Angiogenesis is a complicated process, which is regulated by numerous cytokines and growth factors. Besides, the interaction of endothelial cells with extracellular matrix components, with other cell types and with each other is essential for the formation on new blood vessels. The initiation, continuation and completion of angiogenesis depend on the balance of pro- and antiangiogenic factors in the endothelium microenvironment.