Effects of housing systems and laying phases on external and internal egg quality characteristics of indigenous guinea fowl hens.

The study investigated the effect of housing system and laying phases on the internal and external qualities of guinea fowl eggs laid in three different housing systems. The trial involved the use of 117, 34-wk-old guinea fowl hens which were assigned to three housing types, which were battery cages, deep litter, and deep litter housing systems with free runs, which had the same dimensions as deep litter houses but with free run and open-air space to allow the birds to have free access to soil and exhibit natural behavior. The laying phases of the birds were partitioned into three (36 to 40, 41 to 45, and 46 to 50 wk of age).

Evidence for empagliflozin in heart failure with preserved ejection fraction (HFpEF).

Anker SD, Butler J, Filippatos G, Empagliflozin in heart failure with a preserved ejection fraction. , 2021; 385:1451-61.

Prescribing direct-acting oral anticoagulants - Mind the evidence gap.

Direct-acting oral anticoagulants (DOACs) are licensed for the prevention of thromboembolism in non-valvular atrial fibrillation, amongst other indications. Prescribers use information derived from the summary of product characteristics which is based on the key trials supporting the DOAC's market authorisation. However, prescribers may not be aware of the limitations within these trials regarding underrepresentation of patient populations commonly encountered in clinical practice and how this may adversely impact them.

Sustainable medicines use in clinical practice: A clinical pharmacological view on eco-pharmaco-stewardship.

Climate change continues to pose a dangerous threat to human health. However, not only is health impacted by this crisis, healthcare itself adds to the problem, through significant contributions to greenhouse gas emissions. In the UK, the National Health Service (NHS) is responsible for an estimated 4% of the overall national carbon footprint.