Publications by authors named "E Huisman"

Multiple system atrophy is characterized pathologically by the accumulation of alpha-synuclein (aSyn) into glial cytoplasmic inclusions (GCIs). The mechanism underlying the formation of GCIs is not well understood. In this study, correlative light and electron microscopy was employed to investigate aSyn pathology in the substantia nigra and putamen of post-mortem multiple system atrophy brain donors.

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Article Synopsis
  • Glanzmann thrombasthenia (GT) and Bernard-Soulier syndrome (BSS) are conditions where patients often need platelet transfusions, which can cause problems if they react to donor blood types.
  • Doctors in the Netherlands were surveyed to find out how they handle platelet matches, and many believe it's important to prevent issues with antibodies from forming.
  • The study suggests that most pediatric doctors are already matching blood types when giving transfusions to these patients, and they recommend more matching based on some guidelines.
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Background: Enteral feeding is an essential part of the management of infants with gastroschisis. We hypothesized that exclusive breast milk is associated with improved neonatal outcomes.

Methods: We conducted a retrospective review of infants with uncomplicated gastroschisis through the Canadian Pediatric Surgery Network (CAPSNet) and Canadian Neonatal Network (CNN).

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Article Synopsis
  • - The study examines how bleeding disorders (BDs) affect health-related quality of life (HRQoL) in children and their caregivers, highlighting the need for HRQoL measurement to identify areas needing support and evaluate new treatments.
  • - A scoping review of 53 articles revealed that most research focuses on school-aged boys with hemophilia from Europe and North America, with a significant gap in studies involving younger children and different types of bleeding disorders.
  • - The conclusion stresses the importance of expanding HRQoL research to include a wider range of patients and better statistical methods, as current studies often combine various disorders and utilize multiple questionnaires that limit comparability.
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Introduction: Hemoglobin-based oxygen carriers, for example HBOC-201 (Hemopure), are aimed to bridge acute anemia when blood transfusion is not available or refused by the patient. However, since HBOC-201 appears free in plasma, it interferes with laboratory tests. This study presents an overview of HBOC-201 interference on four commonly used hematology analyzers and suggests treatment monitoring possibilities.

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