Publications by authors named "E Hertel"
Sleep disturbances exacerbate chronic pain, increase psychological load, and increase inflammation. Delayed onset muscle soreness (DOMS) mimics aspects of chronic pain, predominantly affecting peripheral pain mechanisms, while experimental sleep provocations have been shown to impact central pain mechanisms. This study aimed to combine a DOMS model with total sleep deprivation (TSD) to create a novel model affecting both peripheral and central pain mechanisms.
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- - Emerging evidence indicates that quantitative sensory testing (QST) could be useful in predicting how well patients with knee osteoarthritis (OA) will respond to pain relief treatments.
- - This systematic review analyzed various studies from 2000 to 2023, focusing on different treatment methods for OA, and found that QST predicted treatment outcomes in a significant percentage of surgical (81%), pharmaceutical (100%), and exercise-based therapies (50%).
- - The findings suggest that while there is a weak-to-moderate correlation between QST results and treatment success, some patients with OA may be particularly sensitive to pain and may not respond well to standard treatment options.
Article Synopsis
- Sepsis leads to long-term cognitive impairments in survivors, particularly affecting visual attention and working memory.
- Psychophysical tests revealed that these survivors have a reduced working memory capacity compared to healthy controls, impacting their performance on neuropsychological assessments.
- The findings suggest that working memory reductions are significant contributors to cognitive deficits in sepsis survivors and warrant further research to explore underlying mechanisms and potential interventions.
Article Synopsis
- Osteoarthritis (OA) pain varies significantly between individuals, and factors such as psychological well-being, sensory testing, and health-related quality of life play crucial roles in determining pain levels and treatment outcomes.
- This study explored how baseline pain intensity in OA patients relates to their pain after taking a combination of nonsteroidal anti-inflammatory drugs and paracetamol for three weeks, using the KOOS pain score to measure changes.
- Findings revealed that pain catastrophizing scores (PCS) were a significant predictor of both baseline and follow-up pain levels, suggesting that incorporating psychological elements like PCS and pressure pain thresholds (TSP) in treatment plans could be beneficial for managing OA pain.